I have wireguard interface , wg64. example 10.10.10.10, i have PC with wg ip 10.10.10.200.
I have also bridge1 172.30.100.0/24

I want to forward 10.10.10.10:8080 to internal 172.30.100.22:80.

I write /ip/firewall/nat dst-nat
chain=dstnat action=dst-nat to-addresses=172.30.100.22 to-ports=80
protocol=tcp in-interface=wg64 dst-port=8080 log=no log-prefix=""

Please advise how to implement the rules for my case.

Draw a diagram I have no clue how any of these devices are connected either locally or externally. We are not in your mind be much clearer and provide context to such questions.