No. You need some “hardware” to enable eSIM. The older devices do not have the need things on the “motherboard” or modem module, so only choice is to use a special physical/hard SIM card that will allow RouterOS eSIM commands to work.
If you’re not planing on switching carriers, you can just a physical SIM from LMT - this avoid needing any special “physical eSIM” like the 9esim SIM card – but you’re going to need SOME SIM card installed for the modem to work.
There is longer discussion about this topic here:
http://forum.mikrotik.com/t/product-request-mikrotik-should-sell-a-physical-esim-for-older-devices-or-suggest-some-3rd-party-esim/183991/1