Bonding interfaces (Multilink) and dedicate upstream/downstr

Hello,
I saw a bonding tab in the GUI so apparently mikrotik can do multilink.
In location A, I have mikrotik’s 2 ethernet ports connected to Location B mikrotik’s 2 ethernet ports.
Is it possible to multilink the ethernet ports, and set one port to upstream only and the other one downstream only?

Thanks

any ideas?