The TX ones connect to the source(s), the RX ones to the user screen(s), the TX translates the video signal into something that can be transported over an IP network (probably TCP) and the Rx is capable of decoding the something.
The clever part is that the connection is bi-directional and not only the video is sent, but also USB KVM, RS232 and IR signals are exchanged.
[1] The manufacturer of similar HDMI/KVM extenders over IP has this to say about the switches that are compatible: https://eservice.aten.com/eServiceCx/Common/FAQ/view.do?id=6276
essentially, they should be managed, and quite beefy, though there is no Mikrotik model listed there, you can compare the listed ones to Mikrotik products.-
Matrix systems expand on the extender concept by introducing multiple transmitters and receivers that all connect through a local area network (LAN). This enables multiple client stations to manage multiple servers in a more dynamic manner.
KVM over IP matrix systems are highly versatile. An administrator can manage different servers from various control stations, making them suitable for large-scale infrastructure like enterprise data centers.
These systems also tend to offer very high performance, since they rely on well-provisioned LAN connections and hardware transmitters and receivers.
System architecture. With proprietary KVM matrix solutions, chassis ports are
available as inputs only (connected to a Tx), outputs only (connected to a Rx), or
configurable as inputs or outputs. Chassis may have a fixed size or may be
modular. If your system evolves over time, you may face situations where adding
one more computer or console may be costly because the existing chassis is full,
and you must buy a larger chassis or add a second one. Also, distributed
architectures across several buildings may be impossible or only possible at a
significant cost. With KVM over IP matrices, the “matrix chassis” is a network based on the use of COTS switches and routers. This technology is mature,
affordable, and flexible. It has better scalability, supports well distributed
architectures and remote access over the WAN is possible. From the network
perspective, the maximum number of Tx and Rx in a system is theoretically
unlimited. In practice, other factors are limiting their actual number.