Getting Packet Drops

Dear Team,
We have Installed MikroTik on Dell r730 Server for using as NAS but we are facing issue that the MikroTik Server Drops Ping Response of the IP configured on its interface as well as connected devices. We have tried to make changes like MTU Values in MikroTik, Cable Change, physical Connectivity Checking but same status so finally i am writting you about the issue kindly suggest the solution.