This should not be difficult.
Some assumptions.
- You are starting with the default firewall ruleset.
- The ISP router IP range is 192.168.1.0/24 (change below as required to match actual)
- Using winbox to manage router.
In /ip firewall filter
Add a new firewall rule in the forward chain to drop all traffic from LAN to 192.168.1.0/24
/ip firewall filter
add action=drop chain=forward comment="drop all traffic from LAN to 192.168.1.0" \
in-interface-list=LAN dst-address=192.168.1.0/24
Then in winbox move this rule to the end of the forward chain rules. (so, keeping the forward chain rules together)
Test from a LAN client.