Idk how i have blocked my ports in mikrotik 2.2.10 so I need help how to unblock it ?
refer to mikrotik manual help, that can be found :
http://www.mikrotik.com/testdocs/ros/2.9/
or may be this is the answer of your problem:
http://www.mikrotik.com/testdocs/ros/2.9/ip/service.php
please be more specific next time!
look at /ip firewall filter there must me all yout rules that might drop packets on ports