Internet Not allow client use to pop and smtp mail server use outlook.

RouterOS Forwarding Protocols
1

Hi,
I want to permission 50/60 user to access their email use MS Outlook pop/smtp configuration, But they don’t access in internet is it possible i write a rule for this but it don’t work.

/ip firewall address-list
add address=172.17.100.117 list=MailAllow
add address=172.17.100.118 list=InternetAllow
/ip firewall filter
add action=drop chain=forward dst-port=26 protocol=tcp src-address-list=InternetAllow
add action=drop chain=forward dst-port=110 protocol=tcp src-address-list=InternetAllow
add action=drop chain=forward src-address-list=MailAllow
add chain=forward dst-port=26 protocol=tcp src-address-list=MailAllow
add chain=forward dst-port=110 protocol=tcp src-address-list=MailAllow

2

Firewall rules are applied from top, your third rule drops all connections from MailAllow address list and next two rules are not in effect.
To allow connections to ports 110 and 25 (SMTP port is 25, not 26) and block all other connections

add action=drop chain=forward src-address-list=MailAllow

should be last rule