ip flow command is just telling the cisco router what interfaces to watch for netflow/sflow exporting and has no bearing on the connection itself.
You’d have to supply config for both the Cisco interface (sh run int )
And the Mikrotik interface (/int gre export)
Then we might be able to help you figure out the issue - but if config is fine then you’d need to debug on one or the other ends to find out what the error cause is.