Firstable, sorry for my english…
I have 2 sites, in each one I have 1 mikrotik running with Internet, i have create 1 tune VPN but I only can ping from pc site A to router site B, or pc in site B to router site A, but NOT between pc site A to pc site B.
I’m really in problems because I can not solved this issue… can someone help me, please??
If you tell me I can send the pics of my configuration… I really apreciatte your help!!! 
Did you check your routes configuration? You should have a route for each network. Ex.:
Site A network: 192.168.0.0/24
Site B network: 192.168.1.0/24
Let's suppose that your VPN IP local address is 172.1.1.1 and your remote address is 172.1.1.2.
In your routing table you shoud have in router A:
[admin@R1] /ip route> print
0 A S ;;;
192.168.1.0/24 (172.1.1.1) 1
In your routing table you shoud have in router B:
[admin@R1] /ip route> print
0 A S ;;;
192.168.0.0/24 (172.1.1.2) 1
Wrong. I assume the OP is using a pure IPsec (and not GRE/L2TP/whatever over IPsec), and pure (policy-based) IPsec bypasses routing decisions entirely.