Dear all,
I am using Mikrotik(5.20) + Squid Box(ubuntu based)… i am facing an issue that squid is blocking my Media server IP(this i have connected after mikrotik)…
Can any one pl tell…how to exclude a specific ip address(media server) in mikrotik DST-NAT RULE so that mikrotik should not send sharing server request to squid, it should open it directly ..???

Please provide us with your current firewall setup … what is the mediaserver ip?
Im gonna guess that you are using dst-nat to redirect all your traffic to your mikrotik web-proxy and use ubuntu squid box as parent proxy. If so you can exclude an IP by adding src-address to your dst-nat redirect with ! (exclemation mark) … like so for example:
/ip firewall nat add chain=dstnat action=redirect to-ports=8080 protocol=tcp src-address=!192.168.170.4 in-interface=bridge-local dst-port=80
JF.