Mikrotik CHR P10 packet loss

CHR version: 6.46.4 (latest)
When the bandwidth reaches 40Mbps+, packet loss occurs (1-3%)
At first I thought it was an ESXI problem and then replaced it with PVE ,Unfortunately the problem persists


CHR PVE instance

Related threads: http://forum.mikrotik.com/t/mikrotik-chr-p1-licence-packet-loss-fixed/106069/1