Mikrotik doesn't route anymore *SOLVED*

My Friend called me that his Internet is down, and he is not able to connect to the Mikrotik Webfig Administration.
Then I tried to connect from the outside to his Server through RDP, and it works.
From the Server I am able to connect to the Mikrotik through Winbox using the Mac Adress, but I am not able to connect to the Router with the IP Adress.

After checking all Settings, upgraded the Router to 6.4, the Errors still stay the same.
I disabled all Firewall Rules, disabled the Hotspot, but no success.
I can ping every Adress or Website from the Network, it seems that everything on Port 80 is not routed.

In Winbox everything looks to be ok, only in Firewall > Connections there is only 1 established Connection (DHCP Wan Side), and all other Connections are on “syn sent”.
My Friend is actually a 1 Hour drive away, so I would prefer to solve the Problem from the remote Location.

Found the Problem,

seems he wanted to do some Port forwarding, and added a wrong dstnat rule, which seems to routed all Traffic to this Nat Setting.