Outgoing SMTP being blocked

I have 2 servers inside the network that need to connect to a smtp server outside the network. I need to know what setting I should put in the mikrotik to allow these 2 servers to send out smtp.

these are the rules that are setup in the firewall for nat

Flags: X - disabled, I - invalid, D - dynamic
0 chain=srcnat out-interface=Internet action=masquerade

1 chain=dstnat in-interface=Internet protocol=tcp dst-port=3389
action=dst-nat to-addresses=192.168.0.103 to-ports=3389

2 chain=dstnat dst-address=209.40.226.124 protocol=tcp action=dst-nat
to-addresses=192.168.0.250 to-ports=0-65535

3 chain=dstnat dst-address=209.40.226.124 protocol=udp action=dst-nat
to-addresses=192.168.0.250 to-ports=0-65535

4 chain=dstnat dst-address=209.40.226.122 protocol=tcp action=dst-nat
to-addresses=192.168.0.222 to-ports=0-65535

5 chain=dstnat dst-address=209.40.226.122 protocol=udp action=dst-nat
to-addresses=192.168.0.222 to-ports=0-65535

6 chain=dstnat in-interface=Internet protocol=tcp dst-port=34200-34203
action=dst-nat to-addresses=192.168.0.103 to-ports=34200-34203

7 chain=dstnat in-interface=Internet protocol=tcp dst-port=5900
action=dst-nat to-addresses=192.168.0.249 to-ports=5900

No filter rules or Mangle rules

Port 25 is most likely being blocked by your ISP

nope isp has everything open for us. we a t1 coming in. It was working before we replace the router we have with this one.

can you ‘telnet smtpserver 25’ from the internal server?

if not, then disable your rules and retry.

is the default gateway correct?

what error are you getting? is it a SMTP error code or what?

can you trace route to the external smtp server?

Where is you masquerade rule?