HI Guys,
I have 2 mikrotik and I want to establish a point-to-point connection between them.
I have these WAN interface ip 192.168.254.17 for 1 MK and 192.168.254.18 for another.
ip LAN interface172.16.42.254.
Can someone help me
Hard to say. The IP addresses you indicate are private ones, so a connection between the two boxes is only possible if both are in the same private network and the network routes between them. Is that the case, or are these WAN IPs assigned by ISPs?
Sindy tks for you help
both Mikrotik are in the same private network.
OK, so now what exactly do you mean by “point to point connection” 
It may be anything from a plain Ethernet cable between two Ethernet ports of the boxes through PPP L3 tunnels of various kinds to L2 tunnels, ciphered or plaintext. So to choose the right variant, please describe the intended application of the “point to point connection” which cannot be fulfilled by the normal routing between the two.