Route all Office365 traffic via VPN

Hello!
I established connection from mikrotik to L2TP VPN server via l2tp-client connection.
Now I need to route all traffic that goes to MS Office 365 mail service from my network through the VPN tunel.
need help with this issue
Thanks a lot!

make a stright forward firewall rule. Tell what you want to do - and it does the job. Eg, if you want all traffic to mymailserver.mail to route trough a interface - tell the firewall to eather send(route) trough another interface - or make it nat - to that ip/interface.