RouterOS on CRS326 - upgrade from USB flash drive

Usual mode of manual upgrading ROS is to copy npk file to root of device’s storage. After that reboot device and it should pick the file.
The trick in your case is how to move/copy file from flash drive to device’s storage. I don’t think there’s command to actually copy file from one directory (or mounted filesystem) to another inside ROS though. You might get some inspiration for a workaround from this old thread.