If you have some other way to access both devices at the same time, just run Wireshark at the Windows PC to see that it is sending the TCP packets towards port 1723 at the IP address of the Mikrotik, and run /tool sniffer quick port=1723 in a text terminal window at the Mikrotik itself to see whether such packets are coming. If you can see bi-directional communication on TCP, it still doesn’t mean that GRE communication gets through, as many ISPs handle GRE wrong, and as GRE is not really NAT-friendly by nature.
But out of curiosity, what makes you prefer PPTP over at least L2TP/IPsec (let alone IKEv2) once you have Windows 10 as a client? PPTP suffers from problems with GRE plus provides just a caricature of security.