I was already giving the same advice a few years ago, it’s how I work…
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If it’s a bug like the one reported above(¹), you’re fu–ed anyway…
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Make a binary backup
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Make one export
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Schedule the reload on A) REBOOT and on B) after xx minutes
(It depends on how long you think it will take to make the changes, usually 10 minutes is enough)
NOTE: This do not do reboot-loop for reload the backup, since on binary backup reloaded is not present the scheduled reload at reboot. -
Do the work
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Make again one export
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Compare prev/next export for review the differencies
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If all is OK remove scheduled reload on point 3)
(¹) https://forum.mikrotik.com/viewtopic.php?p=1131405#p1131111