Problem solved in my case.
Turn out the problem is the Router OS NTP server
NTP package as no log as stipulate
See : http://wiki.mikrotik.com/wiki/Manual:System/Time
NOTE: the above logging rules work only with the built-in SNTP client, the separate NTP package doesn't have any logging facilities
I turn on log in the client package instead
I receive error on debug NTP mode
That message is explicit:
server-not-synchronized - Leap Indicator field is set to "alarm condition" value, which means that clock on the server has not been synchronized yet.
Turn out the RouterOS time server was not synchronize on the web.
Change the NTP client to good time server and all start to work
I fix the time on the router board itself and all works find