Please check your cisco will actually reply to an ICMP Ping ?
Also check if the interface the IP address 220.127.116.11/24 is attached to is active. If not then the IP may also not be active.
What about pinging 18.104.22.168 ? does this work ? What about traceroute ?
The cisco is physically attached to both subnets so routing should be ok. Does the PC have 22.214.171.124 as it's default gateway ?
The rule is you need a route to the host and the host needs a route back
(and no firewall's stopping your tests)
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Mikrotik Distributor - New Zealand