Hello.

I need to know if i can use Mikrotik Hardware to run multiple CentOS as a guest OS.
Also i want to know if i can use the Mikrotik ethernet port as the CentOS indvidual NIC for each guest VM.

the layout is that if i have a Mikrotic 16 port router, i need to have 10 virtual machine (CentosOS) using one port for each machine for a lab environment.

Thanks.

No.
Mikrotik uses it's own version of Linux called ROS.

I wouldn't be so quick, RouterOS can be host. In x86 version should be KVM and some non-x86 architectures have MetaROUTER (but those are out for CentOS). But with x86 it should probably work, although not exactly with MikroTik hardware (as far as I know, they don't make any x86 devices, except prehistoric RB230), and I'm not sure about exact capabilities of KVM in RouterOS, because I've never tested it myself. Personally I'd rather choose something like ESXi, but feel free to try with RouterOS (system installed from CD will work 24 hours without license).