These values are related to bridge STP. By changing these parameters you push port priority or path-cost (in most cases you should only be using one of them depending on your network's topology) when the port is added to the bridge you specified.
If your L2TP clients are simply PCs or other devices, then you shouldn't change any of these settings since it will not have any effect.
If you connect multiple networks together and have multiple links between these networks, then you might consider changing these values since you can specify which link is going to be your active link.
You can read more about STP here:
https://wiki.mikrotik.com/wiki/Manual:S ... e_Protocol