We have IPSEC VPN connection from Mikrotik to ASA as below

192.168.20.10(LAN-Mikrotikside) <-->220.x.x.x(Mikrotik)<---->213.y.y.y(CiscoASA)<--->10.10.16.120:4444 (server at ASA-side)

The IPsec connections goes down after some time.

I have also tried by changing the lifetime value for both ipsec-peer and ipsec-propsal. but the problem did not solved.

I have also tried by disabling DPD at Mikrotik side using below link but still problem exist.

http://forum.mikrotik.com/viewtopic.php?f=2&t=66178

can anyone point me to right direction ??

We have IPSEC VPN connection from Mikrotik to ASA as below

192.168.20.10(LAN-Mikrotikside) <-->220.x.x.x(Mikrotik)<---->213.y.y.y(CiscoASA)<--->10.10.16.120:4444 (server at ASA-side)

The IPsec connections goes down after some time.

I have also tried by changing the lifetime value for both ipsec-peer and ipsec-propsal. but the problem did not solved.

I have also tried by disabling DPD at Mikrotik side using below link but still problem exist.

http://forum.mikrotik.com/viewtopic.php?f=2&t=66178

can anyone point me to right direction ??

Have you looked at the IPSEC settings on the Cisco? It should work once they are all correct.