I'm having problems on a RB530 with Eth 2. It seems to stop passing traffic now and again (the frequency of outages is increasing). The only way to bring this interface back (it shows normal operation in the CLI/Winbox) is by rebooting. Dis/Enabling doesn't do anything, changing Auto Negotion to manual, 10Mbps vs 100, nothing other than reboot. This RB530 has the 564 daughterboard, and is running 2.9.6. It's only been in the field about a month; and I've had freeze up problems on this board as well. (These seem to have gone away for the moment.)
The only ususual item, perhaps compared to other uses, in our use of this board is power. We are running it on the lower voltage setting via the power plug (not PoE) at 23vdc, as the board is at a 24vdc solar/wind site. The power is being regulated via a LM317 based power supply to keep the voltage at spec.