MikroTik community:
After struggling with MIMO 2x2 and side-by-side dual band (2.4GHz + 5GHz) wireless performance issues, I managed to isolate it down to default antennas, which get installed in aluminum cases. Either it's proximity of them to each other (severe de-tuning and interference) or their build quality , they would never give me a stable bandwidth and connection reliability. Some distributors would even stack four antennas in aluminum enclosure (three antenna mount holes + USB hole) to get MIMO 2x2 for both frequencies. The later, pre-made, solution was the one, that I purchased and deployed to the customer and had to troubleshoot it for poor performance. The only way I could make it stable and perform well was by removing the cover and physically spread antennas apart from each other and the enclosure.
After isolating the issue, my next step was to look for other commercially available antennas, that cover both WiFi bands and try to modify my MikroTik devices. I stumbled upon a reputable antenna manufacturing company called Taoglas and bought come of their antenna products to test them out. With new modifications, which you can see in the included pictures, RB922UAGS-5HPacD + R11e-2HPnD gave me perfect results. There is no interference when all chains are fully active.
Taoglas parts used in my setup:
TG.35.8113 (big flat antenna);
GW.71.5153 (round antenna);
MB.200.C (antenna mount);
I hope you find this information useful.
grg