Dear All,
I have a strange issue. I have a Site to Site Ipsec/IKE2 VPN between 2 mikrotik routers. Main Office CCR1009-8G-1S, Site Office RB4011iGS+ both on v6.49.1

From the site office the users randomly lose connection to a shared folder in the Main office. There is a ping to the Main office and the VPN is established. It happens randomly couple of times per day and sometimes is fine for the whole day. Restarting the Mikrotik fixes it temporarily.
Could you point me in the right direction what could be causing this?

I captured some Wireshark traffic and it seems like an SMB2 issue. Probably I need to change the MSS value

I changed the MSS values but users still experience drops. Any advice?