I was looking for a multi-gig managed PoE switch with at least 8x 2.5G PoE ports and a 10G uplink port.

Does Mikrotik have a 2.5G PoE managed switch with at least 8x 2.5G PoE ports and a 10G uplink port?

No,
Mikrotik does not have a 2.5G PoE managed switch with at least 8x 2.5G PoE ports and a 10G uplink port, yet.
Newest CRS310-8G+2S+IN is 8x 2.5G and 10Gb SFP but no POE.

POE version might become available (or not) but nobody will be able to tell when.
Mikrotik usually does not reveal such info until the device is released.

If mikrotik releases a poe variant of the CRS310-8G+2S+IN we will buy hundreds of them. @Normis do you want to share if this might be in the works?

If mikrotik releases a poe variant of the CRS310-8G+2S+IN we will buy hundreds of them. @Normis do you want to share if this might be in the works?

After the lessons learned of the CRS354...

YOU BUY ONE OF THEM. You beat the hell out of it and make sure it keeps working. Then after you shake out any "undocumented features"... you buy a few. Once you test those... then you move on.

If mikrotik releases a poe variant of the CRS310-8G+2S+IN we will buy hundreds of them. @Normis do you want to share if this might be in the works?

If you open up the new CRS310, you'll see lots of interesting stuff related to POE on the circuit board...

We've had real good luck with the css610 and the crs112 but then again we've been surprised with other mikrotik products in the past.