can I limit website in proxy from hotspot profile

let say I want to create 2 hotspot user with 2 profiles
I have proxy running on the router
and I want to be able to deny access to www.movies.com in profile 1 but not in profile 2

can I do this?
deny access depend on the proflie?

Thanks ,

set up firewall(set the hotspot on extra) and mangle rules with layer7 filter for the subnet you want to block access from. check this example:

https://otorbus.wordpress.com/2015/08/11/mikrotik-block-youtube-or-other-video-streaming-sites-for-specific-ip-at-specific-time-schedule/

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well thanks ,
I will try it and see