A bit problem with routing rule on ros 7.22rc3 and winbox4.0.1

You should report this bug in the 7.22rc thread instead of here. Because 7.22 is still in development and that thread is monitored by the developers.

It's probably a problem with wrong default value in the metadata sent to WinBox. You can manually fix it by setting the chain to user. Or use the unset command in the CLI.

/routing rule print
/routing rule unset 6 chain